Main Line Fertility & Reproductive Medicine vs University of Pennsylvania, Penn Fertility Care
Two fertility clinics in the Philadelphia area, about 8 miles apart. Their CDC live-birth rates at every patient age, what each posts for IVF and other treatments, refund programs and services, side by side and cited.
Main Line Fertility & Reproductive Medicine (Bryn Mawr, PA) and University of Pennsylvania, Penn Fertility Care (Philadelphia, PA) are fertility clinics in the Philadelphia area, about 8 miles apart. For patients under 35, Main Line Fertility & Reproductive Medicine reported a live-birth rate of 38.7% per intended egg retrieval and University of Pennsylvania, Penn Fertility Care reported 52.8% (CDC data for 2022). Main Line Fertility & Reproductive Medicine posts an IVF price of $14,300 on its website. University of Pennsylvania, Penn Fertility Care posts no IVF price on its website. A higher rate can reflect who a clinic treats as much as how well it treats them, and posted prices cover different services, so read the terms below.
Success rates at every age
Each clinic's CDC live-birth rate per intended egg retrieval, for patients using their own eggs, in each age band (2022 data). Read the row for your age. A dash means the CDC reported no rate for that clinic at that age.
For patients under 35, Main Line Fertility & Reproductive Medicine reported a live-birth rate of 38.7% per intended egg retrieval and University of Pennsylvania, Penn Fertility Care reported 52.8% (CDC data for 2022). University of Pennsylvania, Penn Fertility Care reported the higher rate in all 4 age bands the two clinics report.
These are averages for each clinic's own patients, who differ in age, diagnosis and treatment history, so a higher rate can reflect who a clinic treats as much as how well it treats them. The CDC's own guidance says "comparisons between clinics should be made with caution", because clinics "have different patient populations or ART treatment methods". See how to read IVF success rates.
What each clinic posts on its website
Each amount is the clinic's own posted figure, linked to the page it was read on, with what it covers. The two clinics' amounts rarely cover the same services, so we never call one cheaper from posted prices: read the terms, then ask both for an itemized quote.
Main Line Fertility & Reproductive Medicine
IVF, as its website posts it
Main Line Fertility publishes IVF without PGT starting at $14,300 for one cycle. It includes ultrasounds and blood monitoring, egg retrieval, insemination, embryo culture, embryo cryopreservation, and one year of storage. Medications are not included; the clinic says they may add approximately $4,000–$8,000. PGT is a separate option published at $17,300 starting, inclusive of embryo biopsy. The clinic also publishes a broader self-pay single-cycle range of $14,250–$20,000, depending on the treatment plan; that description says fees typically encompass monitoring, laboratory work, retrieval, fertilization, embryo transfer, and follow-up visits, while medications, anesthesia, and genetic testing are usually billed separately. Pricing is presented for Main Line Fertility’s Greater Philadelphia network, which includes the Bryn Mawr, PA location; a Bryn Mawr-specific quote, dated fee schedule, insurance eligibility, and payment requirements are not published.
Read Oct 2, 2026. Full terms on its page
University of Pennsylvania, Penn Fertility Care
Posts no IVF price on its website (read Oct 2, 2026). Its price comes from a quote, usually after a consultation.
Refund programs and multi-cycle packages
How IVF refund programs workMain Line Fertility & Reproductive Medicine
- BUNDL Guard
100% of the program fee back if no live birth; covers up to 3 egg retrievals; medications extra
Price not posted
- BUNDL 1+1 with Success Guard
Unused prepaid cycles refunded after a live birth; covers up to 1 egg retrieval
Price not posted
- BUNDL Basic
A multi-cycle package with no refund; covers up to 3 egg retrievals; medications extra
Price not posted
Read Oct 6, 2026. Full terms on its page
University of Pennsylvania, Penn Fertility Care
- Penn Medicine self-pay multi-cycle IVF packages
A multi-cycle package with no refund
Price not posted
Read Oct 6, 2026. Full terms on its page
Egg freezing
What egg freezing costsMain Line Fertility & Reproductive Medicine
One egg freezing cycle
Includes monitoring and 1 year of storage, then $750 a year
On top: anesthesia
Read Oct 4, 2026. Full terms on its page
University of Pennsylvania, Penn Fertility Care
Posts no egg freezing price on its website (read Oct 4, 2026).
Frozen embryo transfer
What a frozen transfer costsMain Line Fertility & Reproductive Medicine
Frozen embryo transfer
Includes monitoring, ultrasounds, the thaw and the transfer
Read Oct 10, 2026. Full terms on its page
PGT (embryo genetic testing)
What PGT costsMain Line Fertility & Reproductive Medicine
IVF with PGT
Includes embryo biopsy
Read Oct 9, 2026. Full terms on its page
Main Line Fertility & Reproductive Medicine
- From $2,950a cycle
IUI procedure
Includes ultrasounds, sperm wash and insemination
Read Oct 8, 2026. Full terms on its page
Embryo and egg storage
What storage costsMain Line Fertility & Reproductive Medicine
Read Oct 10, 2026. Full terms on its page
Reciprocal IVF
What reciprocal IVF costsMain Line Fertility & Reproductive Medicine
Describes reciprocal IVF as one of its services, without a price (read Oct 11, 2026).
University of Pennsylvania, Penn Fertility Care
No reciprocal IVF price or description we could confirm.
If you are paying without insurance, ask each clinic for a Good Faith Estimate: an itemized list of expected charges it must give you within 3 business days of your request. Two itemized estimates are the only like-for-like price comparison. To see what your own plan would cost, use the IVF cost calculator.
What each clinic offers
From each clinic's own report to the CDC ART Services and Profile dataset. A field marked not reported was left blank in the CDC data.
Where they are, and what insurance must cover
Main Line Fertility & Reproductive Medicine is in Bryn Mawr, PA and University of Pennsylvania, Penn Fertility Care is in Philadelphia, PA, about 8 miles apart. Both are in the Philadelphia metro area. Contact details come from the CDC and may have changed.
Main Line Fertility & Reproductive Medicine
825 Old Lancaster Rd, Suite 170, Bryn Mawr, PA 19010
- Phone
- (484) 380-4879
- Medical director
- Michael J. Glassner, MD
- CDC status
- Open
University of Pennsylvania, Penn Fertility Care
3701 Market St, Suite 800, Philadelphia, PA 19104
- Phone
- (215) 662-6100
- Medical director
- Clarisa R. Gracia, MD
- CDC status
- Open
Insurance law
- Pennsylvania: No state lawNo state law requires it: RESOLVE, the national infertility association, lists no Pennsylvania law requiring insurers to cover IVF, infertility treatment or fertility preservation. Pennsylvania's full answer
The law that applies follows your health plan, not the clinic you choose, and it does not reach self-funded employer plans. See what your insurer or employer covers.
Common questions about Main Line Fertility & Reproductive Medicine and University of Pennsylvania, Penn Fertility Care
Which has the higher IVF success rate, Main Line Fertility & Reproductive Medicine or University of Pennsylvania, Penn Fertility Care?
For patients under 35, Main Line Fertility & Reproductive Medicine reported a live-birth rate of 38.7% per intended egg retrieval and University of Pennsylvania, Penn Fertility Care reported 52.8% (CDC data for 2022). University of Pennsylvania, Penn Fertility Care reported the higher rate in all 4 age bands the two clinics report. These are averages for each clinic's own patients, who differ in age, diagnosis and treatment history, so a higher rate can reflect who a clinic treats as much as how well it treats them.
How much does IVF cost at Main Line Fertility & Reproductive Medicine compared with University of Pennsylvania, Penn Fertility Care?
Main Line Fertility & Reproductive Medicine's website posts $14,300 for IVF (read Oct 2, 2026). University of Pennsylvania, Penn Fertility Care posts no IVF price on its website (read Oct 2, 2026), so its price comes from a quote. A posted price is a starting point: medications, monitoring, anesthesia, embryo freezing and a frozen transfer are often billed separately. If you are paying without insurance, ask each clinic for a Good Faith Estimate: an itemized list of expected charges it must give you within 3 business days of your request.
Do Main Line Fertility & Reproductive Medicine and University of Pennsylvania, Penn Fertility Care offer IVF refund programs?
Main Line Fertility & Reproductive Medicine offers a program that returns money if treatment fails, and University of Pennsylvania, Penn Fertility Care offers multi-cycle packages, with no refund if treatment fails (each clinic's own website, read on Oct 6, 2026). Before you sign up for any program, ask for the written contract: what counts as success, how much comes back, and which medications and procedures are excluded.
Which is the larger clinic, Main Line Fertility & Reproductive Medicine or University of Pennsylvania, Penn Fertility Care?
Main Line Fertility & Reproductive Medicine is the larger clinic: it reported 1,032 cycles to the CDC and University of Pennsylvania, Penn Fertility Care reported 831. Cycle volume shows how busy a clinic is, not how good it is.
How far apart are Main Line Fertility & Reproductive Medicine and University of Pennsylvania, Penn Fertility Care?
Main Line Fertility & Reproductive Medicine is in Bryn Mawr, PA and University of Pennsylvania, Penn Fertility Care is in Philadelphia, PA, about 8 miles apart. Both are in the Philadelphia metro area.
Does insurance cover IVF at Main Line Fertility & Reproductive Medicine and University of Pennsylvania, Penn Fertility Care?
No state law requires it: RESOLVE, the national infertility association, lists no Pennsylvania law requiring insurers to cover IVF, infertility treatment or fertility preservation. State insurance laws reach only fully-insured plans, and 67% of covered US workers are in self-funded employer plans, which set their own fertility benefits whatever the state requires. About 50% of employers with 500 or more workers now cover IVF.