Clomid (clomiphene citrate)
Ovulation induction
Sold as Serophene
Clomid costs $4.08 to $10.91 per 50 mg tablet at the 2 sources that post a cash price, lowest at Mark Cuban Cost Plus Drugs (prices read Oct 4, 2026); a drug-price guide lists $4.50 per 50 mg tablet at an ordinary retail pharmacy; pharmacies themselves pay a national average of $4.21 per tablet to acquire it (CMS NADAC).
A selective estrogen-receptor modulator taken orally to stimulate ovulation, the longest-established oral fertility drug. Used for anovulation and in some unexplained-infertility protocols.
What Clomid costs, by pharmacy
Every cash price we found posted by a pharmacy, TrumpRx.gov or the manufacturer, read on the seller's own page on Oct 4, 2026, compared per one unit and cheapest first. A retail drug-price guide's figure is shown for context.
- Mark Cuban Cost Plus DrugsCash pharmacyClomid 50 mg, 30 tablets: $122.54 (drug $117.54 + $5 pharmacy fee)Shipping $5.25.$4.08read Oct 4, 2026
- Drugs.com price guideRetail price guideClomid 50 mg, 10 tablets: $45.00 for 10$4.50read Oct 4, 2026
- Drugs.com price guideRetail price guideClomiphene citrate (generic) 50 mg, 10 tablets: $69.28 for 10$6.93read Oct 4, 2026
- Amazon PharmacyCash pharmacyClomiphene citrate 50 mg, 5 tablets (generic): $54.55Without Prime; the page shows $18.00 for eligible Prime members.$10.91read Oct 4, 2026
Cash prices only: with insurance that covers fertility drugs you pay your plan's share instead, and most manufacturer programs cannot be combined with insurance. Prices change; each row links to the page it was read on. Compare every IVF medication, or see what a whole cycle's drugs cost after TrumpRx.
The national acquisition cost (CMS NADAC)
The national average price a US retail pharmacy pays to acquire each product, published weekly by CMS. A wholesale floor, not the price you are charged.
- Clomiphene Citrate 50 MG TabNDC 83390010709 · effective Sep 23, 2026$4.21/ ea
Source: CMS National Average Drug Acquisition Cost (NADAC) · as of Sep 23, 2026
Across a whole stimulation cycle, all the medications together typically total $3,000–$7,000, which is the number that matters for a budget. See the full cycle breakdown or how families pay for it.
When it is given
A short course of tablets early in the cycle, usually with follicle monitoring, for timed intercourse or an IUI cycle. Also used in mini-IVF protocols to reduce the injectable load.
What the prescribing information says
The current FDA structured product label, as published through openFDA and DailyMed. Excerpted verbatim, not summarised.
What the FDA label approves it for
INDICATIONS AND USAGE Clomiphene citrate is indicated for the treatment of ovulatory dysfunction in women desiring pregnancy. Impediments to achieving pregnancy must be excluded or adequately treated before beginning clomiphene citrate therapy. Those patients most likely to achieve success with clomiphene therapy include patients with polycystic ovary syndrome (see WARNINGS : Ovarian Hyperstimulation Syndrome ), amenorrhea-galactorrhea syndrome, psychogenic amenorrhea, post-oral-contraceptive amenorrhea, and certain cases of secondary amenorrhea of undetermined etiology. Properly timed coitus in relationship to ovulation is important. A basal body temperature graph or other appropriate tests may help the patient and her physician determine if ovulation occurred. Once ovulation has been established, each course of clomiphene citrate should be started on or about the 5th day of the cycle. Long-term cyclic therapy is not recommended beyond a total of about six cycles (including three ovulatory cycles). (See DOSAGE AND ADMINISTRATION and PRECAUTIONS .) Clomiphene citrate is indicated only in patients with demonstrated ovulatory dysfunction who meet the conditions described below: Patie
Dosage and administration
DOSAGE AND ADMINISTRATION General Considerations The workup and treatment of candidates for clomiphene citrate therapy should be supervised by physicians experienced in management of gynecologic or endocrine disorders. Patients should be chosen for therapy with clomiphene citrate only after careful diagnostic evaluation (see INDICATIONS AND USAGE ). The plan of therapy should be outlined in advance. Impediments to achieving the goal of therapy must be excluded or adequately treated before beginning clomiphene citrate. The therapeutic objective should be balanced with potential risks and discussed with the patient and others involved in the achievement of a pregnancy. Ovulation most often occurs from 5 to 10 days after a course of clomiphene citrate. Coitus should be timed to coincide with the expected time of ovulation. Appropriate tests to determine ovulation may be useful during this time. Recommended Dosage Treatment of the selected patient should begin with a low dose, 50 mg daily (1 tablet) for 5 days. The dose should be increased only in those patients who do not ovulate in response to cyclic 50 mg clomiphene citrate. A low dosage or duration of treatment course is particular
Warnings and cautions
WARNINGS Visual Symptoms Patients should be advised that blurring or other visual symptoms such as spots or flashes (scintillating scotomata) may occasionally occur during therapy with clomiphene citrate. These visual symptoms increase in incidence with increasing total dose or therapy duration. These visual disturbances are usually reversible; however, cases of prolonged visual disturbance have been reported with some occurring after clomiphene citrate discontinuation. The visual disturbances may be irreversible, especially with increased dosage or duration of therapy. Patients should be warned that these visual symptoms may render such activities as driving a car or operating machinery more hazardous than usual, particularly under conditions of variable lighting. These visual symptoms appear to be due to intensification and prolongation of after-images. Symptoms often first appear or are accentuated with exposure to a brightly lit environment. While measured visual acuity usually has not been affected, a study patient taking 200 mg clomiphene citrate daily developed visual blurring on the 7th day of treatment, which progressed to severe diminution of visual acuity by the 10th day
Contraindications
CONTRAINDICATIONS Hypersensitivity Clomiphene citrate is contraindicated in patients with a known hypersensitivity or allergy to clomiphene citrate or to any of its ingredients. Pregnancy Clomiphene citrate use in pregnant women is contraindicated, as clomiphene citrate does not offer benefit in this population. Available human data do not suggest an increased risk for congenital anomalies above the background population risk when used as indicated. However, animal reproductive toxicology studies showed increased embryo-fetal loss and structural malformations in offspring. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential risks to the fetus. (See PRECAUTIONS: Pregnancy ). Liver Disease. Clomiphene citrate therapy is contraindicated in patients with liver disease or a history of liver dysfunction (see also INDICATIONS AND USAGE and ADVERSE REACTIONS ). Abnormal Uterine Bleeding. Clomiphene citrate is contraindicated in patients with abnormal uterine bleeding of undetermined origin (see INDICATIONS AND USAGE ). Ovarian Cysts. Clomiphene citrate is contraindicated in patients with ovarian c
Label for Clomid, source: openFDA structured product labels · as of Oct 4, 2026
What has been reported to the FDA
FAERS is a voluntary reporting system. A high count reflects how widely a drug is used and how often people report, not how dangerous it is, and a report is not proof the drug caused the event.
- abortion spontaneous 110
- drug exposure during pregnancy 107
- nausea 87
- off label use 83
- headache 81
- drug ineffective 74
Source: openFDA FAERS (drug adverse events) · as of Sep 29, 2026
About Clomid
How much does Clomid cost?
Clomid costs $4.08 to $10.91 per 50 mg tablet at the 2 sources that post a cash price, lowest at Mark Cuban Cost Plus Drugs (prices read Oct 4, 2026); a drug-price guide lists $4.50 per 50 mg tablet at an ordinary retail pharmacy; pharmacies themselves pay a national average of $4.21 per tablet to acquire it (CMS NADAC). Across a whole IVF cycle, all the medications together typically total $3,000 to $7,000.
What is Clomid used for in fertility treatment?
A selective estrogen-receptor modulator taken orally to stimulate ovulation, the longest-established oral fertility drug. Used for anovulation and in some unexplained-infertility protocols. A short course of tablets early in the cycle, usually with follicle monitoring, for timed intercourse or an IUI cycle. Also used in mini-IVF protocols to reduce the injectable load.
How is Clomid given?
Oral. A short course of tablets early in the cycle, usually with follicle monitoring, for timed intercourse or an IUI cycle. Also used in mini-IVF protocols to reduce the injectable load.
Other medications in a cycle
- Letrozole (Femara)Ovulation induction (commonly first-line for PCOS)Ovulation induction
- Gonal-f (follitropin alfa)Controlled ovarian stimulation for IVFOvarian stimulation
- Follistim AQ (follitropin beta)Controlled ovarian stimulation for IVFOvarian stimulation
- Menopur (menotropins)Combined FSH and LH activity during stimulationOvarian stimulation