Gonal-f (follitropin alfa)
Controlled ovarian stimulation for IVF
Gonal-f costs $42 per 75 IU at each of the 2 sources that post a cash price (prices read Oct 4, 2026); a drug-price guide lists $236.57 per 75 IU at an ordinary retail pharmacy.
Recombinant follicle-stimulating hormone (FSH) made by EMD Serono, injected daily from a pen or a multi-dose vial to grow multiple follicles during an IVF or egg-freezing stimulation.
What Gonal-f costs, by pharmacy
Every cash price we found posted by a pharmacy, TrumpRx.gov or the manufacturer, read on the seller's own page on Oct 4, 2026, compared per one unit and cheapest first. A retail drug-price guide's figure is shown for context.
- TrumpRx.govGovernment siteGonal-f Redi-ject pen, 300 IU: TrumpRx Price $168.00Cash only; the TrumpRx coupon works at Freedom Fertility and Village Fertility. List price shown: $966.04.$42read Oct 4, 2026
- TrumpRx.govGovernment siteGonal-f Redi-ject pen, 900 IU: TrumpRx Price $504.00Cash only. List price shown: $2,898.12. The 450 IU pen and 450 IU multi-dose vial are $252, the same per IU.$42read Oct 4, 2026
- Mandell's Clinical PharmacyFertility pharmacyGonal-F 900 IU pen: $ 504Estimate; service fee added at checkout. 300 IU pen $168, 450 IU pen or vial $252.$42read Oct 4, 2026
- Drugs.com price guideRetail price guideGonal-f RFF Redi-ject pen, 900 IU: from $2,838.78 for 1.44 milliliters$236.57read Oct 4, 2026
- Drugs.com price guideRetail price guideGonal-f RFF Redi-ject pen, 300 IU: from $990.85 for 0.5 milliliters$247.71read Oct 4, 2026
Cash prices only: with insurance that covers fertility drugs you pay your plan's share instead, and most manufacturer programs cannot be combined with insurance. Prices change; each row links to the page it was read on. Compare every IVF medication, or see what a whole cycle's drugs cost after TrumpRx.
Programs that lower the cost of Gonal-f
Each program's own terms, read on its page. Eligibility is the program's to decide.
- Fertility Instant SavingsEMD Serono
The same fixed cash prices as TrumpRx: Gonal-f $168 (300 IU pen), $252 (450 IU pen or multi-dose vial), $504 (900 IU pen); Cetrotide $22.50; Ovidrel $84, shipped at no cost.
Who qualifies: Anyone 18 or older in the US who pays for these EMD Serono medications out of pocket, with no insurance claim for them. No income test; insurance can still pay for the rest of treatment. Works for IVF, IUI, egg freezing, surrogacy and donation cycles.
How to enroll: A savings card issued instantly online, used at a participating pharmacy: Freedom Fertility, Village Fertility, Alto, Mandell's, Apri, Prima, CVS Specialty or SMP Pharmacy Solutions. Help line 1-866-538-7879.
Read Oct 4, 2026
- Compassionate CareEMD Serono
EMD Serono's deepest self-pay discount; its pages give no amount. The Council of Economic Advisers (May 2026) puts it at $25 per 75 IU of Gonal-f.
Who qualifies: Self-pay patients whose household income qualifies (checked against a tax return), 18 or older, not using insurance for these medications. EMD Serono does not publish the income limit; the White House Council of Economic Advisers describes the income-qualified price as for incomes below 550% of the federal poverty level.
How to enroll: Apply at fertilitysavings.com with a tax return; a decision takes 1 to 5 business days. Eligibility lasts 365 days, then reapply.
Read Oct 4, 2026
- Compassionate CorpsEMD Serono
Free medication, for up to 2 cycles a year.
Who qualifies: Medically retired military members or veterans (or their spouses) made infertile by a service-related injury, needing IVF, not insured for fertility medications and not eligible under the Fertility Veterans Act.
How to enroll: Call Fertility LifeLines at 1-866-538-7879 or apply through fertilitysavings.com; reapply each year.
Read Oct 4, 2026
- Livestrong FertilityLivestrong Foundation, with medication donated by EMD Serono
Free fertility stimulation medication from EMD Serono, plus at least 25% off services at partner clinics.
Who qualifies: A cancer diagnosis whose treatment may affect fertility, lawfully present in the US, at a Livestrong partner clinic. For the person freezing eggs or embryos: household income up to $130,000 single or $170,000 married, with no or limited insurance for it.
How to enroll: Online application at livestrong.org after an eligibility checklist, with a letter from the oncology team; (855) 844-7777.
Read Oct 4, 2026
The national acquisition cost (CMS NADAC)
The national average price a US retail pharmacy pays to acquire each product, published weekly by CMS. A wholesale floor, not the price you are charged.
No CMS acquisition cost for this medication
CMS surveys what retail pharmacies pay, and this medication is filled almost entirely by specialty pharmacies, so NADAC has no row for it. No figure is shown rather than an estimate.
Across a whole stimulation cycle, all the medications together typically total $3,000–$7,000, which is the number that matters for a budget. See the full cycle breakdown or how families pay for it.
When it is given
Daily subcutaneous injections through the stimulation phase of an IVF or egg-freezing cycle, with the dose adjusted at each monitoring scan and blood draw based on how the ovaries respond.
What the prescribing information says
The current FDA structured product label, as published through openFDA and DailyMed. Excerpted verbatim, not summarised.
What the FDA label approves it for
1 INDICATIONS AND USAGE GONAL-f is indicated for: GONAL-f is a gonadotropin indicated for: Women: Induction of ovulation and pregnancy in oligo-anovulatory infertile women for whom the cause of infertility is functional and not due to primary ovarian failure. ( 1.1 ) Development of multiple follicles in ovulatory infertile women as part of Assisted Reproductive Technology (ART) cycles. ( 1.2 ) Men: Induction of spermatogenesis in infertile men with primary and secondary hypogonadotropic hypogonadism for whom the cause of infertility is not due to primary testicular failure. ( 1.3 ) 1.1 Induction of ovulation and pregnancy in oligo-anovulatory infertile women for whom the cause of infertility is functional and not due to primary ovarian failure. 1.2 Development of multiple follicles in ovulatory infertile women as part of an assisted reproductive technology (ART) cycle. 1.3 Induction of spermatogenesis in infertile men with primary and secondary hypogonadotropic hypogonadism for whom the cause of infertility is not due to primary testicular failure.
Dosage and administration
2 DOSAGE AND ADMINISTRATION Induction of Ovulation ( 2.3 ) Initial starting dose of the first cycle - 75 International Units of GONAL-f per day for 14 days, administered subcutaneously Individualize doses after 14 days Do not administer doses greater than 300 International Units per day Development of Multiple Follicles in Assisted Reproductive Technology (ART) ( 2.3 ) Initial starting dose of the first cycle - 150 International Units per day, administered subcutaneously Dosage adjustments after 3 to 5 days and by 75 to 150 International Units at each adjustment Do not administer doses greater than 450 International Units per day Males with Hypogonadotropic Hypogonadism and Azoospermia ( 2.4 ) Use in conjunction with hCG. Prior to concomitant therapy with GONAL-f and hCG, pretreat with 1,000 to 2,250 USP units of hCG alone two to three times per week to achieve normal serum testosterone levels, which may take 3 to 6 months. After normalization of serum testosterone, administer 150 International Units of GONAL-f subcutaneously three times a week and 1,000 USP units of hCG (or the dose required to maintain serum testosterone levels within the normal range) three times a week. 2.1 Imp
Warnings and cautions
5 WARNINGS AND PRECAUTIONS Hypersensitivity Reactions and Anaphylaxis: If occurs, initiate appropriate therapy including supportive measures, and discontinue GONAL-f ( 5.1 ) Ovarian Hyperstimulation Syndrome: If serious, stop gonadotropins, including hCG, and determine if the woman needs to be hospitalized. Treatment is primarily symptomatic and consists of bed rest, fluid and electrolyte management, and analgesics ( 5.2 ) Pulmonary and Vascular Complications: In women with recognized risk factors, the benefits of induction of ovulation and ART need to be weighed against the risks. During or after use of GONAL-f, monitor for venous or arterial thromboembolic events ( 5.3 ) Ovarian Torsion: Early diagnosis and immediate detorsion limit damage to the ovary due to reduced blood supply ( 5.4 ) Abnormal Ovarian Enlargement: If the ovaries are abnormally enlarged on the last day of GONAL-f therapy, inform women not to administer hCG and to avoid intercourse ( 5.5 ) Multi-fetal Gestation and Births: The rate of multiple births is dependent on the number of embryos transferred. Advise the woman and her partner of the potential risk of multi-fetal gestation and birth before beginning therap
Contraindications
4 CONTRAINDICATIONS GONAL-f is contraindicated in women and men who exhibit: Prior hypersensitivity to recombinant FSH products or one of their excipients. Reactions have included anaphylaxis [see Warning and Precautions (5.1) ] High levels of FSH indicating primary gonadal failure The presence of uncontrolled non-gonadal endocrinopathies (for example, thyroid, adrenal, or pituitary disorders) Sex hormone dependent tumors of the reproductive tract and accessory organs Tumors of pituitary gland or hypothalamus GONAL-f is also contraindicated in women who exhibit: Abnormal uterine bleeding of undetermined origin Ovarian cyst or enlargement of undetermined origin GONAL-f is contraindicated in women and men who exhibit ( 4 ): Prior hypersensitivity to recombinant FSH products or one of their excipients High levels of FSH indicating primary gonadal failure Uncontrolled non-gonadal endocrinopathies Sex hormone dependent tumors of the reproductive tract and accessory organs Tumors of pituitary gland or hypothalamus GONAL-f is also contraindicated in women who exhibit ( 4 ): Abnormal uterine bleeding of undetermined origin Ovarian cyst or enlargement of undetermined origin
Label for Gonal-f, source: openFDA structured product labels · as of Oct 4, 2026
What has been reported to the FDA
FAERS is a voluntary reporting system. A high count reflects how widely a drug is used and how often people report, not how dangerous it is, and a report is not proof the drug caused the event.
- ovarian hyperstimulation syndrome 687
- ascites 223
- abdominal pain 128
- abortion spontaneous 123
- abdominal distension 116
- nausea 101
Source: openFDA FAERS (drug adverse events) · as of Sep 29, 2026
About Gonal-f
How much does Gonal-f cost?
Gonal-f costs $42 per 75 IU at each of the 2 sources that post a cash price (prices read Oct 4, 2026); a drug-price guide lists $236.57 per 75 IU at an ordinary retail pharmacy. Across a whole IVF cycle, all the medications together typically total $3,000 to $7,000.
Is there a savings program for Gonal-f?
Yes: Fertility Instant Savings (EMD Serono): The same fixed cash prices as TrumpRx: Gonal-f $168 (300 IU pen), $252 (450 IU pen or multi-dose vial), $504 (900 IU pen); Cetrotide $22.50; Ovidrel $84, shipped at no cost. Compassionate Care (EMD Serono): EMD Serono's deepest self-pay discount; its pages give no amount. The Council of Economic Advisers (May 2026) puts it at $25 per 75 IU of Gonal-f. Compassionate Corps (EMD Serono): Free medication, for up to 2 cycles a year. Livestrong Fertility (Livestrong Foundation, with medication donated by EMD Serono): Free fertility stimulation medication from EMD Serono, plus at least 25% off services at partner clinics. Each program states its own eligibility; read it on the program's page before you fill the prescription.
What is Gonal-f used for in fertility treatment?
Recombinant follicle-stimulating hormone (FSH) made by EMD Serono, injected daily from a pen or a multi-dose vial to grow multiple follicles during an IVF or egg-freezing stimulation. Daily subcutaneous injections through the stimulation phase of an IVF or egg-freezing cycle, with the dose adjusted at each monitoring scan and blood draw based on how the ovaries respond.
How is Gonal-f given?
Injectable. Daily subcutaneous injections through the stimulation phase of an IVF or egg-freezing cycle, with the dose adjusted at each monitoring scan and blood draw based on how the ovaries respond.
Other medications in a cycle
- Follistim AQ (follitropin beta)Controlled ovarian stimulation for IVFOvarian stimulation
- Menopur (menotropins)Combined FSH and LH activity during stimulationOvarian stimulation
- Letrozole (Femara)Ovulation induction (commonly first-line for PCOS)Ovulation induction
- Clomid (clomiphene citrate)Ovulation inductionOvulation induction