Cetrotide (cetrorelix)

GnRH antagonist that blocks a premature LH surge

Sold as generic cetrorelix acetate

Updated weekly · checked 3 h ago

$22.50lowest posted cash price per 0.25 mg dose

$306.06per vial, what pharmacies pay

617FAERS reports (all-time)

Cetrotide costs $22.50 to $59.88 per 0.25 mg dose at the 3 sources that post a cash price, lowest at TrumpRx.gov (prices read Oct 4, 2026); a drug-price guide lists $316.68 per 0.25 mg dose at an ordinary retail pharmacy; pharmacies themselves pay a national average of $306.06 per vial to acquire it (CMS NADAC).

Cost

What Cetrotide costs, by pharmacy

Every cash price we found posted by a pharmacy, TrumpRx.gov or the manufacturer, read on the seller's own page on Oct 4, 2026, compared per one unit and cheapest first. A retail drug-price guide's figure is shown for context.

Where, and the product as listedPer 0.25 mg dose

TrumpRx.govGovernment site
Cetrotide 0.25 mg (prefilled syringe and vial): TrumpRx Price $22.50
Cash only. List price shown: $316.12.
$22.50
read Oct 4, 2026
Mandell's Clinical PharmacyFertility pharmacy
Cetrotide 0.25 mg kit: $ 22.50
Estimate; service fee added at checkout.
$22.50
read Oct 4, 2026
Mark Cuban Cost Plus DrugsCash pharmacy
Cetrorelix acetate 0.25 mg kit (generic): $59.88 (drug $44.88 + $15 pharmacy fee)
Refrigerated shipping $55 per order.
$59.88
read Oct 4, 2026
Drugs.com price guideRetail price guide
Cetrotide 0.25 mg, 1 kit: from $316.68 for 1 powder for injection
$316.68
read Oct 4, 2026

Cash prices only: with insurance that covers fertility drugs you pay your plan's share instead, and most manufacturer programs cannot be combined with insurance. Prices change; each row links to the page it was read on. Compare every IVF medication, or see what a whole cycle's drugs cost after TrumpRx.

Savings

Programs that lower the cost of Cetrotide

Each program's own terms, read on its page. Eligibility is the program's to decide.

Fertility Instant SavingsEMD Serono
The same fixed cash prices as TrumpRx: Gonal-f $168 (300 IU pen), $252 (450 IU pen or multi-dose vial), $504 (900 IU pen); Cetrotide $22.50; Ovidrel $84, shipped at no cost.
Who qualifies: Anyone 18 or older in the US who pays for these EMD Serono medications out of pocket, with no insurance claim for them. No income test; insurance can still pay for the rest of treatment. Works for IVF, IUI, egg freezing, surrogacy and donation cycles.
How to enroll: A savings card issued instantly online, used at a participating pharmacy: Freedom Fertility, Village Fertility, Alto, Mandell's, Apri, Prima, CVS Specialty or SMP Pharmacy Solutions. Help line 1-866-538-7879.
Read Oct 4, 2026
Compassionate CareEMD Serono
EMD Serono's deepest self-pay discount; its pages give no amount. The Council of Economic Advisers (May 2026) puts it at $25 per 75 IU of Gonal-f.
Who qualifies: Self-pay patients whose household income qualifies (checked against a tax return), 18 or older, not using insurance for these medications. EMD Serono does not publish the income limit; the White House Council of Economic Advisers describes the income-qualified price as for incomes below 550% of the federal poverty level.
How to enroll: Apply at fertilitysavings.com with a tax return; a decision takes 1 to 5 business days. Eligibility lasts 365 days, then reapply.
Read Oct 4, 2026
Compassionate CorpsEMD Serono
Free medication, for up to 2 cycles a year.
Who qualifies: Medically retired military members or veterans (or their spouses) made infertile by a service-related injury, needing IVF, not insured for fertility medications and not eligible under the Fertility Veterans Act.
How to enroll: Call Fertility LifeLines at 1-866-538-7879 or apply through fertilitysavings.com; reapply each year.
Read Oct 4, 2026
Livestrong FertilityLivestrong Foundation, with medication donated by EMD Serono
Free fertility stimulation medication from EMD Serono, plus at least 25% off services at partner clinics.
Who qualifies: A cancer diagnosis whose treatment may affect fertility, lawfully present in the US, at a Livestrong partner clinic. For the person freezing eggs or embryos: household income up to $130,000 single or $170,000 married, with no or limited insurance for it.
How to enroll: Online application at livestrong.org after an eligibility checklist, with a letter from the oncology team; (855) 844-7777.
Read Oct 4, 2026

What pharmacies pay

The national acquisition cost (CMS NADAC)

The national average price a US retail pharmacy pays to acquire each product, published weekly by CMS. A wholesale floor, not the price you are charged.

Package (NDC description)Per unit

Cetrotide 0.25 MG Vial
NDC 44087122501 · effective Jan 29, 2025
$306.06
/ ea

Source: CMS National Average Drug Acquisition Cost (NADAC) · as of Jan 29, 2025

Across a whole stimulation cycle, all the medications together typically total $3,000–$7,000, which is the number that matters for a budget. See the full cycle breakdown or how families pay for it.

In a cycle

When it is given

Started partway through the stimulation phase and continued daily until the trigger, in an antagonist protocol.

FDA label

What the prescribing information says

The current FDA structured product label, as published through openFDA and DailyMed. Excerpted verbatim, not summarised.

What the FDA label approves it for

INDICATIONS AND USAGE Cetrotide ® (cetrorelix acetate for injection) is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.

Dosage and administration

DOSAGE AND ADMINISTRATION Ovarian stimulation therapy with gonadotropins (FSH, hMG) is started on cycle Day 2 or 3. The dose of gonadotropins should be adjusted according to individual response. Cetrotide ® (cetrorelix acetate for injection) 0.25 mg may be administered subcutaneously once daily during the early- to mid-follicular phase. Cetrotide ® 0.25 mg is administered on either stimulation day 5 (morning or evening) or day 6 (morning) and continued daily until the day of hCG administration. When assessment by ultrasound shows a sufficient number of follicles of adequate size, hCG is administered to induce ovulation and final maturation of the oocytes. No hCG should be administered if the ovaries show an excessive response to the treatment with gonadotropins to reduce the chance of developing ovarian hyperstimulation syndrome (OHSS). Administration Cetrotide ® 0.25 mg can be administered by the patient herself after appropriate instructions by her doctor. Directions for using Cetrotide ® 0.25 mg with the enclosed needles and pre-filled syringe: Wash hands thoroughly with soap and water. Flip off the plastic cover of the vial and wipe the aluminum ring and the rubber stopper with

Warnings and cautions

WARNINGS Cetrotide ® (cetrorelix acetate for injection) should be prescribed by physicians who are experienced in fertility treatment. Before starting treatment with Cetrotide ® , pregnancy must be excluded (see CONTRAINDICATIONS and PRECAUTIONS ).

Contraindications

CONTRAINDICATIONS Cetrotide ® (cetrorelix acetate for injection) is contraindicated under the following conditions: Hypersensitivity to cetrorelix acetate, extrinsic peptide hormones or mannitol. Known hypersensitivity to GnRH or any other GnRH analogs. Known or suspected pregnancy, and lactation (see PRECAUTIONS ). Severe renal impairment

Label for Cetrotide, source: openFDA structured product labels · as of Oct 4, 2026

Reported adverse events

What has been reported to the FDA

FAERS is a voluntary reporting system. A high count reflects how widely a drug is used and how often people report, not how dangerous it is, and a report is not proof the drug caused the event.

617reports, all-time

435flagged serious

ovarian hyperstimulation syndrome 135
drug ineffective 42
premature ovulation 40
abortion spontaneous 39
ascites 28
abdominal distension 27

Source: openFDA FAERS (drug adverse events) · as of Sep 29, 2026

Common questions

About Cetrotide

How much does Cetrotide cost?

Is there a savings program for Cetrotide?

Yes: Fertility Instant Savings (EMD Serono): The same fixed cash prices as TrumpRx: Gonal-f $168 (300 IU pen), $252 (450 IU pen or multi-dose vial), $504 (900 IU pen); Cetrotide $22.50; Ovidrel $84, shipped at no cost. Compassionate Care (EMD Serono): EMD Serono's deepest self-pay discount; its pages give no amount. The Council of Economic Advisers (May 2026) puts it at $25 per 75 IU of Gonal-f. Compassionate Corps (EMD Serono): Free medication, for up to 2 cycles a year. Livestrong Fertility (Livestrong Foundation, with medication donated by EMD Serono): Free fertility stimulation medication from EMD Serono, plus at least 25% off services at partner clinics. Each program states its own eligibility; read it on the program's page before you fill the prescription.

What is Cetrotide used for in fertility treatment?

A gonadotropin-releasing-hormone antagonist used for the same job as ganirelix: preventing ovulation from happening before the retrieval. Which of the two a clinic uses is largely protocol and supply preference. Started partway through the stimulation phase and continued daily until the trigger, in an antagonist protocol.

How is Cetrotide given?

Injectable. Started partway through the stimulation phase and continued daily until the trigger, in an antagonist protocol.

Other medications in a cycle

Posted cash prices are each seller's own published figure on the date shown; your price depends on the pharmacy, the quantity and your insurance. NADAC is the national average price a pharmacy pays to acquire a drug, not the price you are charged. Dosing here is quoted from the FDA label and is not a prescription: your protocol comes from your clinic. IVFcost.co is an informational data platform, not a medical provider, clinic, or laboratory. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Success rates depend heavily on individual circumstances and are not a promise of any outcome. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the clinic's own current figures.